The initials BRCA2 may be best known for a gene associated with many cases of breast cancer, and the protein encoded by the BRCA2 gene is critical to repairing breaks in DNA.
Molecular & Computational biology
Aug 13, 2021
0
289
BRCA1, a protein that is well-known for its role in hereditary breast cancer, is an important part of the cellular system that repairs double-strand DNA breaks. Now, researchers from Japan have discovered a new way in which ...
Biotechnology
Jul 13, 2021
0
11
Telomeres are large nucleoproteins structures that cap the ends of chromosomes in eukaryotic cells. When a cell divides, a small portion of the telomere is lost due to the inherently incomplete process of genome replication. ...
Biotechnology
Apr 22, 2021
0
197
From cancer treatment to sunlight, radiation and toxins can severely damage DNA in both harmful and healthy cells. While the body has evolved to efficiently treat and restore damaged cells, the mechanisms that allow this ...
Molecular & Computational biology
Apr 15, 2021
0
150
Reconstitution of the activation of the MLH1–MLH3 endonuclease shows how crossovers are formed during meiosis.
Molecular & Computational biology
Aug 20, 2020
0
2
As chromosomes go, X and Y make an unlikely pair. The X is large and contains thousands of genes critical for life. The Y, by contrast, is little more than a nub. Its main purpose is to provide the instructions for initiating ...
Biotechnology
May 28, 2020
4
93
Columbia scientists have captured the first images of a new gene editing tool that could improve upon existing CRISPR-based tools. The team developed the tool, called INTEGRATE, after discovering a unique "jumping gene" in ...
Biotechnology
Dec 18, 2019
0
602
A team of scientists has identified how damaged DNA molecules are repaired inside the human genome, a discovery that offers new insights into how the body works to ensure its health and how it responds to diseases that stem ...
Molecular & Computational biology
Dec 5, 2019
0
24
An interdisciplinary team of researchers at the Hong Kong University of Science and Technology (HKUST) unraveled how a toxin released by Escherichia coli (E. coli) – a human gut bacteria, is connected to colorectal cancer, ...
Biochemistry
Sep 17, 2019
0
89
About 15 years ago, UNC Lineberger's Dale Ramsden, Ph.D., was looking through a textbook with one of his students when they stumbled upon a scientific mystery.
Cell & Microbiology
Nov 16, 2018
2
202
