To understand why some cancer cells resist radiotherapy, an international team of researchers has used crystallography to "photograph" the first moments of the molecular ballet that allows these cells to repair their DNA. ...
Molecular & Computational biology
Oct 9, 2018
0
7
Johns Hopkins scientists have developed a streamlined method and accompanying efficiency "rules" for introducing new DNA sequences into cells after using the gene-cutting tool known as CRISPR. The scientists say the method, ...
Biotechnology
Dec 1, 2017
0
40
Researchers from the University of Seville at the Andalusian Centre for Molecular Biology and Regenerative Medicine have discovered that in eukaryotic cells, the proximity of the genes to the pores in the nuclear membrane ...
Cell & Microbiology
Nov 17, 2017
0
129
A groundbreaking and surprising discovery provides a major conceptual change of what is most important to cells: the fidelity of the DNA transcription process - accurately copying the DNA message into RNA, the precursor to ...
Cell & Microbiology
Oct 4, 2017
0
12
Researchers from several Russian institutes, including MIPT, have found out how prolonged exposure to ionizing radiation affects human stem cells. They discovered that it causes a cell cycle delay, which leads to faster repairs ...
Cell & Microbiology
Aug 25, 2017
0
6
All cells are confronted with DNA damage, for example by exposure of the skin to UV rays, chemical byproducts of nerve cells consuming sugar, or immune cells destroying bacteria. If these DNA lesions are not - or badly - ...
Cell & Microbiology
Jun 13, 2017
0
183
Breaks in DNA can wreak havoc in the body, giving rise to cancer and other health problems. Yet sometimes cells rupture their own DNA for a good reason.
Cell & Microbiology
Apr 17, 2017
0
6
Tufts University researchers have discovered a possible explanation for the occurrence of a genetic error that causes over a dozen neuromuscular and neurodegenerative disorders, including Huntington's disease, myotonic dystrophy ...
Biotechnology
Dec 5, 2016
0
20
Double-stranded breaks in DNA can be detected with several technologies. Doing so in plants is exceptionally difficult, but GUIDE-Seq shows promise in new studies.
Biotechnology
Sep 22, 2016
0
256
Increased sea temperatures could dramatically enhance and accelerate radiation-induced DNA effects in marine invertebrates, a new study suggests.
Environment
Aug 23, 2016
0
0
