Trapped in a microscopic cage made of strands of DNA, molecules of a life-saving drug course through the bloodstream of a cancer patient. Only when receptors on the strands sense they've arrived at the right location—cancer ...
Bio & Medicine
Oct 27, 2022
0
25
Researchers at the Francis Crick Institute have uncovered how the double helix structure of DNA is opened to allow DNA replication. The work could lead to further studies to better understand this process including how it ...
Molecular & Computational biology
Jun 16, 2022
0
15
New findings reveal an advanced, unexpected two-way communication between the function and organization of chromosomes in the cell nucleus. Previous research shows that the organization of chromosomal DNA into loops regulate ...
Cell & Microbiology
Jun 13, 2022
0
66
The molecules of life, DNA, replicate with astounding precision, yet this process is not immune to mistakes and can lead to mutations. Using sophisticated computer modeling, a team of physicists and chemists at the University ...
General Physics
May 5, 2022
3
3338
Imagine Bach's "Cello Suite No. 1" played on a strand of DNA.
Bio & Medicine
Mar 3, 2022
1
327
When people think of DNA, they visualize a string-like double helix structure. In reality, the DNA double helix in cells is supercoiled and constrained into loops. This supercoiling and looping are known to influence every ...
Molecular & Computational biology
Sep 28, 2021
0
527
Researchers have analyzed the three-dimensional structure of a protein that suppresses the development of colorectal polyposis, MUTYH, at the atomic level and clarified the repair mechanism for DNA mispairings by MUTYH. Since ...
Biotechnology
Aug 2, 2021
0
82
DNA is composed of nucleobases represented by the letters A, T, G and C. They form the basis of the genetic code and are present in all living beings. But in a bacteriophage, another base, represented by the letter Z, exists. ...
Cell & Microbiology
Jul 9, 2021
0
221
Breeding better crops through genetic engineering has been possible for decades, but the use of genetically modified plants has been limited by technical challenges and popular controversies. A new approach potentially solves ...
Molecular & Computational biology
Jul 1, 2021
0
10
The (when stretched) two-meter-long DNA molecule in each human cell is continuously being unpacked and packed again to enable the expression of genetic information. When genes must be accessed for transcription, the DNA double ...
Molecular & Computational biology
Apr 13, 2021
0
18
