Biologists reveal how gyrase resolves DNA entanglements

Picture in your mind a traditional "landline" telephone with a coiled cord connecting the handset to the phone. The coiled telephone cord and the DNA double helix that stores the genetic material in every cell in the body ...

Scientists unravel key steps in the road to DNA repair

Researchers from Tokyo Metropolitan University have been studying DNA repair by homologous recombination, where the RecA protein repairs breaks in double-stranded DNA by incorporating a dangling single-strand end into intact ...

Art with DNA—digitally creating 16 million colors by chemistry

The DNA double helix is composed of two DNA molecules whose sequences are complementary to each other. The stability of the duplex can be fine-tuned in the lab by controlling the amount and location of imperfect complementary ...

New method can manipulate the shape and packing of DNA

A human cell harbors roughly 2 meters of DNA, encompassing the essential genetic information of an individual. If one were to unwind and stretch out all the DNA contained within a single person, it would span a staggering ...

Researchers advance DNA nanostructure stability

Researchers at the University at Albany's RNA Institute have demonstrated a new approach to DNA nanostructure assembly that does not require magnesium. The method improves the biostability of the structures, making them more ...

Researchers shed new light on the motor of DNA replication

DNA replication is the process whereby cells make an exact copy of their DNA before cell division. A key part of the intricate DNA replication machinery is a molecular motor called CMG, which has the vital task of separating ...

Breaking bonds: Double-helix unzipping reveals DNA physics

Accurately reconstructing how the parts of a complex molecular are held together knowing only how the molecule distorts and breaks up—this was the challenge taken on by a research team led by SISSA's Cristian Micheletti ...

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