Nucleotide excision repair (NER) is a critical DNA repair pathway that plays a key role in maintaining transcription and genome integrity by removing bulky DNA lesions.
Cell & Microbiology
Dec 8, 2022
0
71
The body needs a lot of blood. In humans, 200 billion new erythrocytes—or red blood cells—are generated daily by erythropoiesis, a multi-step process starting from blood-related stem cells, requiring rigorous maintenance ...
Cell & Microbiology
Nov 29, 2022
0
26
All living cells harbor nuclei—key biological structures that play an important role in information storage, retrieval, and duplication of genetic information. In mammals, these nuclei possess the nuclear envelope (NE)—the ...
Cell & Microbiology
Oct 27, 2022
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16
The enzyme HDAC10 is involved in a variety of cellular processes associated with the development of a number of diseases. However, it is often not known exactly what role HDAC10 plays in the disease process. Scientists from ...
Biochemistry
Oct 12, 2022
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28
Recent advances in imaging technology have made it possible to visualize intracellular dynamics, which offers a better understanding of several key biological principles for accelerating therapeutic development. Fluorescent ...
Biochemistry
Sep 8, 2022
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89
A multidisciplinary team of Indiana University researchers have discovered that the motion of chromatin, the material that DNA is made of, can help facilitate effective repair of DNA damage in the human nucleus—a finding ...
Cell & Microbiology
Sep 2, 2022
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163
Researchers have shown that a protein called fascin acts in the control center of cancer cells and influences their ability to repair themselves, grow and move, according to a study published today in eLife.
Cell & Microbiology
Aug 30, 2022
0
49
Using an innovative new technique, scientists at Duke-NUS Medical School and their collaborators have identified thousands of previously unknown DNA sequences in the human genome that code for microproteins and peptides potentially ...
Cell & Microbiology
Aug 25, 2022
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37
DNA replication and repair happens thousands of times a day in the human body and most of the time, people don't notice when things go wrong thanks to the work of Replication protein A (RPA), the "guardian of the genome." ...
Molecular & Computational biology
Aug 10, 2022
0
14
About 15 years ago, a group of researchers discovered mutant zebrafish. The eyes of these zebrafish did not develop correctly, resulting in significantly smaller eyes than those of wild zebrafish. Now, one of these researchers—Prof. ...
Cell & Microbiology
Aug 9, 2022
0
68
