RNA plays a central role in biology, but there is still much to learn about the molecule's life cycle in the cell. In recent years, scientists have devised methods that can take snapshots of messenger RNAs (mRNAs) scattered ...
Biotechnology
Apr 11, 2023
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14
Therapeutics that use mRNA—like some of the COVID-19 vaccines—have enormous potential for the prevention and treatment of many diseases. These therapeutics work by shuttling mRNA "instructions" into target cells, providing ...
Bio & Medicine
Apr 3, 2023
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28
By inspecting the body's immune response at a molecular level, a research team has developed a new way to test patients for COVID-19. Their method can potentially catch infections a matter of hours after exposure—far earlier ...
Cell & Microbiology
Feb 27, 2023
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105
Researchers from Tokyo Metropolitan University and RIKEN CSRS have developed a new analytical platform based on liquid chromatography, mass spectrometry and software analysis that quantifies the structure of messenger RNA–based ...
Biochemistry
Feb 13, 2023
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10
In the cell, messenger RNAs—or mRNAs—are translated into proteins and eventually degraded, but the relationship between translation and mRNA decay remains cloudy. FMI researchers developed an innovative tool to control ...
Cell & Microbiology
Feb 6, 2023
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5
Synthetic mRNAs are explored rigorously for their potential as an effective genetic vector for basic research and clinical applications. Natural mRNAs have a structure on their leading (5') ends—called the 5' cap—that ...
Biotechnology
Feb 3, 2023
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3
A research team led by Georgia Tech Professor Phil Santangelo has developed an improved mRNA treatment that is designed to be used in a common nebulizer for a more efficient inhalable delivery of the medicine.
Bio & Medicine
Dec 9, 2022
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69
Messenger RNA (mRNA) are biological molecules that transfer the information coded by genes in the nucleus to the cytoplasm for protein synthesis by ribosomes. mRNA sequences can be designed to encode specific proteins; the ...
Bio & Medicine
Nov 10, 2022
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30
An important component of the vaccines protecting people against SARS-CoV-2 virus and its variants are lipid nanoparticles, or LNPs. These circular particles carry therapeutic mRNA payloads, the snippets of genetic material ...
Bio & Medicine
Sep 23, 2022
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80
Circular ribonucleic acids (circRNAs) are a promising platform for gene expression studies as a stable and prevalent ribonucleic acid in eukaryotic cells, which arise from back-splicing. In a new report now published in Nature ...
