Electron cryo-tomography (cryo-ET) is emerging as a powerful technique to provide detailed 3D images of cellular environments and enclosed biomolecules. However, one of the challenges of the methodology is the identification ...
Cell & Microbiology
May 15, 2023
0
224
Scientists at EPFL have developed PeSTo, an AI model that can predict, with high confidence, the binding interfaces of proteins when they bind other proteins, nucleic acids, lipids, ions, and small molecules. The model's ...
Biotechnology
May 10, 2023
0
191
Antibiotic resistance is a global health threat. In 2019 alone, an estimated 1.3 million deaths were attributed to antibiotic resistant bacterial infections worldwide. Looking to contribute a solution to this growing problem, ...
Cell & Microbiology
Mar 31, 2023
0
75
Recent findings by UCSF and Arc Institute scientists open up new possibilities for overcoming a fundamental challenge in drug discovery. There can be a tradeoff between optimizing a drug's key-in-a-lock fit with its target ...
Cell & Microbiology
Dec 8, 2022
0
56
The better we understand cellular processes such as RNA regulation, the better molecular therapies can be developed. Until now, it has been especially difficult to track the regulation of non-coding RNA, which is RNA that ...
Cell & Microbiology
Nov 14, 2022
0
89
The presence of ions affects the structure and dynamics of water on a multitude of length and time scales. New results from ultrafast spectroscopy and theoretical analyses show that the water environment of specific pairs ...
Analytical Chemistry
Oct 12, 2022
0
25
A simple two-carbon compound may have been a crucial player in the evolution of metabolism before the advent of cells, according to a new study published October 4 in the open access journal PLOS Biology, by Nick Lane and ...
Evolution
Oct 4, 2022
1
909
,Researchers from the Max Planck Institute for Dynamics and Self-Organization (MPI-DS) in Göttingen, Germany, and Delft University of Technology, the Netherlands, have developed a new theoretical method to study mixtures ...
Molecular & Computational biology
Jul 26, 2022
0
29
Proteins are existential building blocks of life that also have numerous functions in plants. An average plant cell contains more than 20 billion protein molecules that maintain cellular metabolism and stabilize their structure. ...
Plants & Animals
Jun 16, 2022
0
35
The body's ability to respond to various types of stress is essential for maintaining health, and failure of such adaptive stress responses can trigger or worsen numerous diseases. New research led by investigators at Massachusetts ...
Cell & Microbiology
Apr 5, 2022
0
386
