Study shows how cells prevent harmful extra copies of DNA

A protein that prepares DNA for replication also prevents the replication process from running out of control, according to a new study by Weill Cornell Medicine researchers. The work, published Jan. 5 in Molecular Cell, ...

Scientists unveil the functional landscape of essential genes

A team of scientists at Whitehead Institute and the Broad Institute of MIT and Harvard have systematically evaluated the functions of more than 5,000 essential human genes using a novel, pooled, imaged-based screening method. ...

New model for reproduction of E. coli bacteria

With a new model, AMOLF researchers reveal how single-celled organisms like bacteria coordinate growth, cell division and DNA replication. Bacteria reproduce via growth and cell division. During each cycle of growth and division, ...

Replication protein A and WAS protein partner to fix damaged DNA

DNA replication and repair happens thousands of times a day in the human body and most of the time, people don't notice when things go wrong thanks to the work of Replication protein A (RPA), the "guardian of the genome." ...

Study finds why many IVF embryos fail to develop

In humans, a fertilized egg is no guarantee of reproductive success. Most embryos stop developing and perish within days of fertilization, usually because they have an abnormal number of chromosomes. Now, researchers at Columbia ...

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