During embryonic development, the entire nervous system, the skin and the sensory organs emerge from a single sheet of cells known as the ectoderm. While there have been extensive studies of how this sheet forms all these ...
Cell & Microbiology
Oct 17, 2019
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70
How do temporal variations in protein concentrations affect biology? It's a question that biologists have only recently begun to address, and the findings are increasingly showing that random temporal changes in the amount ...
Cell & Microbiology
Sep 26, 2019
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58
Scientists have long sorted cells into different varieties based on their appearance under a microscope or, for differences that are more visually subtle, based on the behavior of a handful of genes. But in a bid to reveal ...
Cell & Microbiology
May 28, 2019
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66
Groundbreaking research by Sarah Hainer, an assistant professor of gene expression and cell fate in the University of Pittsburgh Department of Biological Sciences, and Thomas G. Fazzio of the University of Massachusetts Medical ...
Cell & Microbiology
Apr 8, 2019
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5
Toggling the functions of a protein that regulates gene expression during cellular reprogramming ensures cell fate conversion, an A*STAR study has found.
Cell & Microbiology
Nov 16, 2018
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7
The development of an adult organism starts with a fertilized egg that differentiates into hundreds of specialized cell types comprising tissues and organs. How these cell fate changes happen is a subject of research interest. ...
Cell & Microbiology
Oct 3, 2018
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9
As plants stretch toward the summer sun, they are marching toward one of the most important decisions of their lives—when to flower. Too early, and they might miss out on key pollinators. Too late, and an early frost could ...
Biotechnology
Aug 6, 2018
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77
Scientists often talk about cell fate and commitment in terms of mechanisms that control gene expression (transcription factors, chromatin remodeling, etc.). But by studying Diamond-Blackfan anemia (DBA), rare genetic blood ...
Cell & Microbiology
Mar 19, 2018
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22
Both cell type and developmental stage can be deduced from measurements of chromatin accessibility in thousands of single cells, researchers at EMBL and the University of Washington show. They used this approach to uncover ...
Cell & Microbiology
Mar 14, 2018
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19
St. Jude Children's Research Hospital scientists have determined how a protein's disordered region serves as a molecular rheostat to help regulate cell survival.
Biochemistry
Mar 6, 2018
0
60
