Researchers at the Technion – Israel Institute of Technology and EMBL Hamburg have discovered remarkable molecular properties of an antimicrobial peptide from the skin of the Australian toadlet. The discovery could inspire ...
Molecular & Computational biology
Jan 14, 2021
0
148
Amyloids refer to abnormal fibrous extracellular and proteinaceous deposits found in organs and tissues that form insoluble constructs that are resistant to degradation. Their formation can accompany disease, where each disease ...
In the human body, proteins sometimes occur in fibrillar aggregates called amyloids. Although certain amyloids are known to have a biological function, amyloid formation is often associated with pathologies, including Alzheimer's ...
Bio & Medicine
Aug 3, 2020
0
6
Amyloids, abnormal fibrillar aggregates of proteins, are associated with various disorders such as Alzheimer's disease. Therefore, an in-depth understanding of the mechanisms of amyloid formation is critical for developing ...
Space Exploration
Jun 16, 2020
0
7
EPFL scientists have developed powerful tools to unmask the diversity of amyloid fibrils, which are associated with Alzheimer's disease and other neurodegenerative disorders. The scientists made the breakthrough by developing ...
Bio & Medicine
Mar 12, 2020
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57
Rice University researchers have found a way to track the formation of soluble amyloid beta peptide aggregates implicated in the onset of Alzheimer's disease.
Biochemistry
Sep 23, 2019
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81
Patients with type 1 diabetes have to regularly inject themselves with insulin, a hormone that helps their cells absorb glucose from the bloodstream. Another hormone called glucagon, which has the opposite effect, is given ...
Molecular & Computational biology
Jun 24, 2019
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1
A team of researchers affiliated with several institutions in France has found that amyloid fibrils lit with near-infrared radiation emit a dim, near-infrared signal. In their paper published in the journal Nature Photonics, ...
While amyloid plaques have long been closely associated with mechanisms driving Alzheimer's disease, visualizing how amyloid proteins assemble continues to prove difficult. The nanometer-sized amyloid fibrils are only a fraction ...
Optics & Photonics
Mar 26, 2019
0
5
Alzheimer's disease is caused by aggregates of amyloid-β (Aβ) peptides. This aggregation is accelerated at the cell membrane surface. Using molecular dynamics simulations and NMR experiments, the research group at ExCELLS ...
Biochemistry
Jan 2, 2019
0
108
