Researchers have discovered ways to convert inhibitor-style targeted cancer drugs into small molecules known as degraders, which help destroy cancer-promoting proteins in cells.
Biochemistry
Apr 11, 2024
0
34
Researchers at the University of Toronto and Sinai Health have created a new platform to identify proteins that can be co-opted to control the stability of other proteins—a new but largely unrealized approach to the treatment ...
Cell & Microbiology
Mar 22, 2024
0
30
Scientists at The Institute of Cancer Research, London, have created a compound that destroys a protein involved in driving cancers, including B-cell lymphoma.
Biochemistry
Apr 26, 2023
0
51
On August 29, 2022, a research team led by Prof. Wang Xiaoxi from the China Academy for Rural Development and School of Public Affairs of Zhejiang University, and Prof. Yuan Changzheng from the School of Public Health of ...
Environment
Nov 2, 2022
0
2
Scientists from the group of Professor Dr. Thorsten Hoppe at the Cologne Cluster of Excellence for Aging Research CECAD have found that in the nematode C. elegans, the perception of changes in ambient temperature via a defined ...
Cell & Microbiology
Oct 7, 2022
0
10
New Jersey Institute of Technology (NJIT) researchers have unveiled a new lab technique they say represents a "paradigm shift" in how pharmaceutical laboratories test and produce new protein-based drugs, such as therapeutic ...
Biochemistry
Sep 27, 2022
0
64
Researchers at the University of Toronto have discovered how mitochondrial turnover—a critical cellular function—begins.
Cell & Microbiology
Aug 22, 2022
1
159
Nitrogen (N) deficiency first affects the N uptake and assimilation systems of plants. Nitrate, the main source of plant N, is absorbed and transported by nitrate transporters. Nitrate can be metabolized directly in the roots ...
Molecular & Computational biology
Aug 18, 2022
0
4
When plants are under drought stress, a large amount of the stress hormone abscisic acid (ABA) is produced to help them resist drought stress. In recent years, studies have found that ubiquitination mediated protein degradation ...
Plants & Animals
Apr 11, 2022
0
18
Proteins are the building blocks of all living things. A vast amount research takes place on how these proteins are made and what they do, from enzymes that carry out chemical reactions to messengers that transmit signals ...
Molecular & Computational biology
Nov 17, 2021
0
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