Chrysanthemum, celebrated for its ornamental, medicinal, and beverage value, faces significant threats from bacterial and fungal infections, particularly black spot disease caused by Alternaria alternate, which leads to severe ...
Plants & Animals
Apr 3, 2024
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1
Internal browning (IB) is a significant post-harvest issue in pineapples, impacting fruit quality and leading to substantial losses, yet its mechanism remains poorly understood. Studies have shown that the accumulation of ...
Molecular & Computational biology
Feb 29, 2024
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1
You'd think the complex flavor in a quality cup of tea would depend mainly on the tea varieties used to make it. But a study appearing in the journal Current Biology shows that the making of a delicious cup of tea depends ...
Cell & Microbiology
Feb 15, 2024
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42
Tea anthracnose significantly impacts China's tea production, with no effective control methods currently available. Research has shifted towards phenolamides, secondary metabolites with potential disease resistance properties. ...
Molecular & Computational biology
Feb 1, 2024
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1
The gut microbiome is so useful to human digestion and health that it is often called an extra digestive organ. This vast collection of bacteria and other microorganisms in the intestine helps us break down foods and produce ...
Cell & Microbiology
Jan 4, 2024
0
113
Autophagy, a eukaryotic mechanism for breaking down cellular components, is a vital process in lytic organelles such as vacuoles in yeast and plants, and lysosomes in animals. Research has predominantly focused on the model ...
Molecular & Computational biology
Dec 21, 2023
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1
A new study conducted by pre-Ph.D. researcher Pablo S. Valera demonstrates the potential of surface-enhanced Raman spectroscopy (SERS) to explore metabolites secreted by cancer cells in cancer research.
Bio & Medicine
Dec 18, 2023
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48
Plants have evolved fiendishly complicated metabolic networks. For years, scientists focused on how plants make secondary metabolites, the compounds that plants produce to enhance their defense and survival mechanisms.
Molecular & Computational biology
Dec 18, 2023
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246
Investigators at the University of Kansas have played a key role in deciphering a previously unidentified cluster of genes responsible for producing sartorypyrones, a chemical made by the fungal pathogen Aspergillus fumigatus, ...
Biochemistry
Nov 21, 2023
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67
Plants produce a dizzying array of chemical compounds known as secondary metabolites, which help them flourish under fluctuating environmental conditions. Some of these metabolites defend against insect attack, while others ...
Plants & Animals
Oct 31, 2023
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1
Metabolites are the intermediates and products of metabolism. The term metabolite is usually restricted to small molecules. A primary metabolite is directly involved in normal growth, development, and reproduction. Alcohol is an example of a primary metabolite produced in large-scale by industrial microbiology. A secondary metabolite is not directly involved in those processes, but usually has an important ecological function. Examples include antibiotics and pigments. Some antibiotics use primary metabolites as precursors, such as actinomycin which is created from the primary metabolite, tryptophan.
Examples of primary metabolites produced by industrial microbiology:
The metabolome forms a large network of metabolic reactions, where outputs from one enzymatic chemical reaction are inputs to other chemical reactions.
Metabolites from chemical compounds, whether inherent or pharmaceutical, are formed as part of the natural biochemical process of degrading and eliminating the compounds. The rate of degradation of a compound is an important determinant of the duration and intensity of its action. Profiling metabolites of pharmaceutical compounds, drug metabolism, is an important part of drug discovery, leading to an understanding of any undesirable side effects.
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