After two decades in the United States, Martin Hetzer returned home to Austria in 2023 to become the 2nd President of the Institute of Science and Technology Austria (ISTA). A year into his new role, the molecular biologist ...
Cell & Microbiology
Apr 4, 2024
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47
Messenger RNA became a household term when it was used as the backbone of the first COVID-19 vaccines, especially after the Nobel Prize was awarded to two mRNA pioneers at the University of Pennsylvania.
Biotechnology
Apr 3, 2024
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6
In a typical cell, genes encoded in DNA are used to make messenger RNA (mRNA), which is used to make proteins, and this process of gene expression keeps the cell running. Gene expression is regulated in each cell such that ...
Cell & Microbiology
Mar 11, 2024
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2
Researchers who work with tiny drug carriers known as lipid nanoparticles have developed a new type of material capable of reaching the lungs and the eyes, an important step toward genetic therapy for hereditary conditions ...
Bio & Medicine
Mar 4, 2024
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55
The secrets of photosynthesis have been discovered at the atomic level, shedding important new light on this plant super-power that greened the Earth more than a billion years ago.
Plants & Animals
Mar 4, 2024
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44
In a significant leap forward in the realm of regenerative medicine, a team at the Terasaki Institute for Biomedical Innovation has introduced a pioneering approach to mRNA therapy using microspheres made of gelatin methacryloyl ...
Bio & Medicine
Feb 29, 2024
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1
Vaccines and therapies based on messenger RNA could be more readily delivered due to a non-toxic polymer that protects RNA and controls its release inside cells.
Bio & Medicine
Feb 16, 2024
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57
One of the ways cells in different kinds of tissue communicate is by exchanging RNA molecules. In experiments with roundworms of the species Caenorhabditis elegans, researchers at the State University of Campinas (UNICAMP) ...
Cell & Microbiology
Feb 15, 2024
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68
Genetic expression, often leading to protein synthesis, requires a complex coordination of molecular machinery across several stages. A vital step in protein-coding gene expression is messenger RNA (mRNA) export, which involves ...
Cell & Microbiology
Feb 8, 2024
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15
The functioning of certain regions of a few genes in cetaceans (whales, porpoises and dolphins) may explain why the Blue whale (Balaenoptera musculus) can reach lengths of up to 30 meters—almost 10 m more than a bus—while ...
Plants & Animals
Jan 22, 2024
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2
Messenger ribonucleic acid (mRNA) is a molecule of RNA encoding a chemical "blueprint" for a protein product. mRNA is transcribed from a DNA template, and carries coding information to the sites of protein synthesis: the ribosomes. Here, the nucleic acid polymer is translated into a polymer of amino acids: a protein. In mRNA as in DNA, genetic information is encoded in the sequence of nucleotides arranged into codons consisting of three bases each. Each codon encodes for a specific amino acid, except the stop codons that terminate protein synthesis. This process requires two other types of RNA: transfer RNA (tRNA) mediates recognition of the codon and provides the corresponding amino acid, while ribosomal RNA (rRNA) is the central component of the ribosome's protein manufacturing machinery.
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