A recent UCLA study demonstrates a new process for screening T cells, part of the body's natural defenses, for characteristics vital to the success of cell-based treatments. The method filters T cells based on the receptor ...
Bio & Medicine
11 hours ago
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14
Researchers have discovered ways to convert inhibitor-style targeted cancer drugs into small molecules known as degraders, which help destroy cancer-promoting proteins in cells.
Biochemistry
Apr 11, 2024
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24
A recent breakthrough sheds light on how the malaria parasite, Plasmodium falciparum, invades human red blood cells. The study, led by the Swiss Tropical and Public Health Institute (Swiss TPH) and Griffith University's Institute ...
Cell & Microbiology
Apr 3, 2024
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0
For the first time, scientists from the University of Cologne (UoC) have developed artificial nucleotides, the building blocks of DNA, with several additional properties in the laboratory, which could be used as artificial ...
Biotechnology
Mar 8, 2024
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89
Helicases are enzymes that unwind DNA and RNA. They're central to cellular life, implicated in a number of cancers and infections—and, alas, extraordinarily difficult to target with drugs.
Biochemistry
Mar 7, 2024
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31
Vanderbilt scientist Houra Merrikh led a team of researchers who discovered the first anti-evolution chemical compound that prevents drug resistance development in bacteria. The compound is also a drug development platform ...
Biochemistry
Feb 29, 2024
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15
An online platform powered by deep learning can predict the makeup of new psychoactive substances to help law enforcement in the fight against dangerous drugs.
Analytical Chemistry
Feb 29, 2024
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13
A research team from the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences / IOCB Prague has developed a novel computational method that can accurately describe how proteins interact with molecules ...
Analytical Chemistry
Feb 20, 2024
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23
In nature, organic molecules are either left- or right-handed, but synthesizing molecules with a specific "handedness" in a lab is hard to do. Make a drug or enzyme with the wrong "handedness," and it just won't work. Now ...
Analytical Chemistry
Jan 10, 2024
0
100
Aptamers, nucleic acids capable of selectively binding to viruses, proteins, ions, small molecules, and various other targets, are garnering attention in drug development as potential antibody substitutes for their thermal ...
Cell & Microbiology
Jan 2, 2024
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