M1 and M2 are activated macrophages that protect our immune system and maintain homeostasis. Interestingly, they are characterized by distinct and opposing phenotypes. M1 macrophages are known for their bactericidal and tumoricidal ...
Biochemistry
Mar 28, 2023
0
52
The invention of scanning probe microscopy (SPM) techniques, including scanning tunneling microscopy (STM) and atomic force microscopy (AFM), has led to a paradigm shift in the visualization and understanding of surface structures ...
Analytical Chemistry
Jan 18, 2023
0
6
Details of a major, updated online resource to help biomedical researchers use the best small-molecule reagents for their experiments have been published.
Biochemistry
Dec 20, 2022
0
5
Lunar regolith is a layer of loosely-packed rocky grains deposited on the lunar surface, whose physical and chemical properties are important for deciphering the geologic history and formulating lunar spacecraft design. Probing ...
Space Exploration
Aug 29, 2022
0
40
Experts in biomedical research are calling for better use of chemical probes to improve our understanding of protein function and the foundations on which much of modern drug discovery and development are based.
Biochemistry
Jul 6, 2022
0
37
Fluorophores, a chemical compound that can emit light, can be used as fluorescent labels for bioimaging, and fluorescent probes to detect a wide range of chemical species and physical parameters.
Materials Science
Nov 29, 2021
0
10
Until now, observing subatomic structures was beyond the resolution capabilities of direct imaging methods, and this seemed unlikely to change. Czech scientists, however, have presented a method with which they became the ...
General Physics
Nov 11, 2021
0
2086
The team used a high-resolution atomic force microscope (AFM) operating in a controlled environment at Princeton's Imaging and Analysis Center. The AFM probe, whose tip ends in a single copper atom, was moved gradually closer ...
Materials Science
Oct 4, 2021
0
5478
Researchers use synthesized small molecule tools, known as chemical probes, with druglike properties to identify specific types of proteins in order to find potential new drug leads. However, currently-available technologies ...
Biochemistry
Sep 9, 2021
0
82
In the perpetual arms races between bacteria and human-made antibiotics, there is a new tool to give human medicine the edge, in part by revealing bacterial weaknesses and potentially by leading to more targeted or new treatments ...
Biochemistry
May 27, 2021
0
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