The capacity to regulate the biodistribution of therapeutics is a highly desired feature that can limit the side effects of many drugs. In a new study in Scientific Reports, Noah Joseph, and a team of biotechnology and nanoscience ...
The effectiveness of any drug molecule depends on how well it interacts with the internal environment inside our body. Its pharmacokinetic (PK) properties determine how successfully it escapes degrading enzymes as it travels ...
Biochemistry
Oct 10, 2023
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54
Antibody treatments may be able to activate the immune system to fight diseases like Parkinson's, Alzheimer's and colorectal cancer, but they are less effective when they bind with themselves and other molecules that aren't ...
Biotechnology
Sep 11, 2023
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23
Investigators led by Shana Kelley, Ph.D., the Neena B. Schwartz Professor of Chemistry, Biomedical Engineering, and of Biochemistry and Molecular Genetics, have developed a novel approach for identifying sequences of artificial ...
Biochemistry
Jul 27, 2023
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39
A team of researchers has developed an electronic biosensor based on DNA aptamers that can detect biomarkers in whole blood samples without the addition of reagents. As the team explains in the journal Angewandte Chemie International ...
Biochemistry
Apr 6, 2023
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33
An MUSC Hollings Cancer Center research team has created what team members believe to be among the first small molecules designed to stimulate immune cells to fight cancer. More importantly, these compounds inhibit a specific ...
Biochemistry
Feb 28, 2023
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124
Like the Roadrunner outwitting Wile E. Coyote, SARS-CoV-2 (the infectious virus responsible for COVID-19) keeps mutating, generating new variants that can slip from the grip of a well-trained immune system or a well-aimed ...
Biochemistry
Sep 9, 2022
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119
Antibodies are among the most frequently used tools in the biosciences, as they enable researchers to identify molecules. However, many commercial antibodies are not specific enough, with the result that they do not recognize ...
Cell & Microbiology
Jul 8, 2022
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13
A team of scientists has created a powerful new method for generating protein drugs. Using computers, they designed molecules that can target important proteins in the body, such as the insulin receptor, as well as vulnerable ...
Biochemistry
Mar 25, 2022
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24
A new study shows how antibodies select the antigens that they bind to, as they navigate the surface of pathogens like coronaviruses. Researchers from KTH Royal Institute of Technology and Karolinska Institutet have created ...
Molecular & Computational biology
Mar 24, 2022
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